It's conceivable, and I've been thinking all along that it's ignition-related. However, Zed has done quite a few tests to eliminate most variables in that scenario. The only other ignition stuff I can think of is poor grounds, but I think that's been covered as well. We should note that the spark plugs are grounded through the block, so the block must be well-grounded. Otherwise, you're robbing power from the spark. With that said, it really sounded like there was not enough advance at part-throttle but it seems as though adding vac advance didn't help, either. At this point, I would do what I can to alleviate the issue. It doesn't matter so much as to why this or that, but what can I do to make it run right. Maybe Zed's engine is not similar to other engines because there are some unknown modifications? Who knows! What I would be doing, with all other options exhausted, is seeing if I can make any adjustments that make it run like I want. I will repeat, though, take a look at your valve lash! Although no one seems to understand the importance of this, valve lash affects valve timing. If you have a tight or loose valve(s), you are putting in more/less air-fuel mixture into the cylinder, the effects of which are most prominent at part-throttle! Uneven mixture distribution can lead to misfires in certain cylinders, the effects of which would be drowned out by the other "good" (compression and valve lash) cylinders. Basically, you may have 4 cylinders firing evenly, but the other 2 are misfiring, giving you problems. An engine with the same setup, but 6 "good" cylinders will not have a problem. This really seems like one of those extensive, time-consuming, head-bashing problems that is being caused by some little, minor adjustment out of tolerance.